Beijing Protocol: haploidentical hematopoietic stem cell transplant
Haploidentical stem cell transplant
Some evidence dates from earlier years. Confirm the latest information with the hospital.
At a glance
A haploidentical donor hematopoietic stem cell transplant system covering leukemia and severe aplastic anemia.
Why here
- Uses haploidentical (partially matched) donors, widening donor availability compared with fully matched transplant.
- A non-ex-vivo T-cell-depleted haploidentical transplant system built around immune tolerance and immune reconstitution.
- The system has been adopted by multiple centres in China and extended to centres in Italy, France and elsewhere.
- Covers transplant indications including leukemia and severe aplastic anemia, with individualised protocols by disease, condition and age.
Evidence and data
3-year overall survival 74–79% for leukemia treated with haploidentical transplant
Hospital-published statement/public data. Not a treatment promise; outcomes vary.
3-year overall survival 86–89% for severe aplastic anemia treated with haploidentical transplant
Hospital-published statement/public data. Not a treatment promise; outcomes vary.
Related work cited in 40 international guidelines/consensus statements (Europe/US and other regions)
Hospital-published statement/public data. Not a treatment promise; outcomes vary.
More than 100 centres in China have implemented the Beijing Protocol
Hospital-published statement/public data. Not a treatment promise; outcomes vary.
Suitable and not suitable
- Suitable
- Requires hospital assessment based on disease type, disease status, age and donor status.
- Not suitable
- Not for self-assessment; eligibility is determined by the hospital.
This is not a self-assessment tool; the hospital decides on eligibility after review.
Treatment and stay
Usually includes pre-transplant assessment, donor preparation and collection, transplant with inpatient monitoring, and post-discharge follow-up. The actual stay must be assessed by the hospital for each case.
- Pre-treatment assessment
- Treatment / procedure
- Inpatient observation
- Follow-up
Cost range
No public data yet — we update this as hospitals publish information.
- Medication and cell preparation
- Transplant / infusion
- Hospital stay and monitoring
- Tests and laboratory work
- Follow-up visits
- Management of complications
Published item prices are not a total treatment price. A case-specific estimate must come from the hospital.
International patients
International patient acceptance is to be confirmed with the hospital.
Sources and updates
1 update record(s)
- · Added
Frequently asked questions
- How is haploidentical transplant different from a matched transplant?
- A haploidentical transplant uses a half-matched donor (often a parent, child or sibling), while a matched transplant requires a fully HLA-matched donor. The transplant team decides based on the condition and matching results.
- Where does the donor come from, and do family members need matching tests?
- Donors are usually sought among family members with HLA matching tests. If no suitable family donor is found, the hospital assesses other donor sources. Matching and selection are arranged by the transplant team.
- What is the risk of graft-versus-host disease (GVHD), and how is it managed?
- GVHD is a complication that requires monitoring after transplant; risk and symptoms vary by patient. Hospitals usually have prevention, monitoring and treatment protocols; the transplant team assesses the specific risk and management.
- What preparation is needed before transplant?
- Preparation usually includes medical records and test results, infection screening, organ-function assessment, psychological assessment, and non-medical arrangements such as visa and travel. The hospital provides the specific checklist after assessment.
- How long is the hospital stay, and what should be monitored after discharge?
- The hospital stay varies with the transplant plan, donor situation and complications. After discharge, follow-up, infection prevention and medication management are usually needed; the hospital decides based on recovery.
- How can international patients start?
- Start by preparing diagnosis, medical records and test results, then use the hospital or our planning tool to understand remote assessment and travel arrangements. See the visa guide for visa and invitation-letter requirements. Acceptance and arrangements are confirmed by the hospital.
Credential basis
- Haploidentical hematopoietic stem cell transplant · Hospital-reported · Verified: 2026-10-23 · Source
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